Patton was born in Jackson, Mississippi but raised in Plano, Texas. She attended Southern Methodist University in Dallas, graduating with a BFA in Theatre in 2007.
In May 2004, following her first year in university, Patton took part in CBS' Soap Star Screen Test, a nationwide audition contest for university students to win a role on the soap opera The Young and the Restless. Patton won the contest alongside Iman Nazemzadeh. In 2008, Patton had a starring role in The WB's web series Sorority Forever and a role in the independent film Commander and Chief.
Patton was cast for many television series including the soap opera The Bold and the Beautiful. She was cast as Iris West in The Flash for The CW. BuddyTV ranked her #5 on its "TV's 100 Sexiest Women of 2014" list. In May 2015, Patton ranked No. 61 in the Maxim Hot 100 List.
In 2017, along with her Arrowverse co-stars Patton launched Shethority ("She + Authority"), an online global collective described as "a positive place for women and the feminine to inspire, empower, and share." Active members of the initiative include Danielle Panabaker, Melissa Benoist, Chyler Leigh, Caity Lotz, Maisie Richardson-Sellers, Tala Ashe, Emily Bett Rickards Juliana Harkavy, and Katie Cassidy. Through social media, women share their own stories and experiences on dealing with self-acceptance, homophobia, sexual harassment at the workplace. Shethority has its own clothing line, which all the money collected will be donated to non-profit organizations fighting for girls and women rights, such as Girls Not Brides and Girls, Inc.
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